Solid Pseudopapillary Neoplasm of the Pancreas Associated with Familial Adenomatous Polyposis
نویسندگان
چکیده
منابع مشابه
Solid Pseudopapillary Neoplasm of the Pancreas
SPN is a rare neoplasm that affects mainly young women. Despite this feature, SPN have been seen in both genders, multiple races, and at a wide range of ages. The genetic mechanism behind the development of SPN is distinct from the more lethal ductal carcinoma of the pancreas. This difference is reflected in the favorable outcome for patients with SPN. Surgery is typically curative in patents w...
متن کاملThe pancreas in familial adenomatous polyposis.
Familial adenomatous polyposis is an archetypal disease illustrating the genetic basis of human cancer. The adenomatous polyposis coli gene functions as a tumor suppressor with hundreds of known mutations that result in a defective adenomatous polyposis coli protein. In addition to the certain fate of colon cancer without colectomy, patients with familial adenomatous polyposis are also at incre...
متن کاملIntraductal papillary mucinous neoplasm of the pancreas in a patient with attenuated familial adenomatous polyposis.
A 67 year old man with a clinical diagnosis of attenuated familial adenomatous polyposis (AFAP) and a past history of synchronous colon cancers in the transverse colon was also found to have an intraductal papillary mucinous neoplasm (IPMN) of the pancreas. In addition, several foci of heterotopic gastric oxyntic mucosa were noted in the duodenum, interspersed with flat and polypoid adenomas. T...
متن کاملSolid Pseudopapillary Neoplasm of the Pancreas: Analysis of Seven Cases
BACKGROUND The purpose of this study was to describe as well as compare our surgical treatment experiences of solid pseudopapillary neoplasms (SPN) of the pancreas and to provide a review of the literature. METHODS A retrospective analysis of data from Vilnius University Hospital Santariskiu Klinikos (VUH SK) and of the literature, which was researched using Karger Publishers, Springer Scienc...
متن کاملThe Histological Origin of Solid-Pseudopapillary Neoplasm of the Pancreas
Solid-pseudopapillary neoplasm of the pancreas (SPNP), as a distinct tumor, often occurred in young female patients with both exocrine and endocrine differentiation. Our aim was to define the SPNP histogenesis and investigate the relationships between its histological origin and the sexual hormone receptors. 20 tumor samples were subjected to the analysis of immunohistologic staining patterns a...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 2015
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.54.4061